The Research Behind GHK-Cu
GHK-Cu is one of the most studied peptides in dermatology. Here's a selection of published, peer-reviewed research on its wound healing, anti-inflammatory, and collagen-rebuilding properties.
Wound Healing & Skin Repair
Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International, 2015.
Pickart L. The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, 2008.
Maquart FX, et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters, 1988.
Anti-Inflammatory Effects
Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences, 2018.
Canapp SO Jr, et al. The effect of topical tripeptide-copper complex on healing of ischemic open wounds. Veterinary Surgery, 2003.
Collagen Synthesis
Pollard JD, et al. Synthetic GHK-Cu enhances dermal wound healing. Journal of Experimental Dermatology, 2005.
Siméon A, et al. Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. J Invest Dermatol, 2000.